Toothache Plant (Spilanthes Oleracea) - Start Toothache Plant seeds and grow this helpful and attractive plant in the herb garden! Toothache Plant is a tender perennial that is commonly used to treat toothaches along with other mouth, throat, and gum conditions. The leaves and flowers can be chewed to have a mildly anesthetizing effect. This medicinal herb also has anti-bacterial and anti-fungal properties, and it enhances the immune system. The leaves are often eaten raw and taste good in salads.